Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 5/20 | 0.43 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.43 |
| ▸ | AGER | Q15109 | 1/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11707759 | 0.90 | MCHR1 (0.49) | MAPTMCOLN3GLAMCHR1MEN1 | |
| SCHEMBL11705623 | 0.89 | MAPT (0.46) | MAPTMCOLN3GLAMCHR1MEN1 | |
| SCHEMBL11707596 | 0.88 | MCHR1 (0.55) | MAPTMCOLN3GLAMCHR1MEN1 | |
| SCHEMBL11706344 | 0.87 | MCHR1 (0.57) | MAPTMCOLN3GLAMCHR1MEN1 | |
| SCHEMBL11150677 | 0.85 | MAPT (0.48) | MAPTMCOLN3GLACNR2C5AR1 | |
| SCHEMBL11710341 | 0.84 | TDP1 (0.56) | MEN1KMT2ACYP2C19CA12CA9 | |
| SCHEMBL11704486 | 0.81 | MCHR1 (0.55) | MAPTMCOLN3GLAMCHR1MEN1 | |
| SCHEMBL11704033 | 0.80 | CNR2 (0.45) | KMT2APSEN1PSEN2APH1BNCSTN | |
| Ditolamide SCHEMBL2110790 | 0.79 | CA9 (0.64) | GLAMEN1KMT2ACNR2CA12 | |
| SCHEMBL11751198 | 0.79 | MCHR1 (0.49) | MAPTMCOLN3GLAMCHR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4022828-A | BIS-(SULFONAMIDO)-SULFIDES | UNIVERSAL OIL PRODUCTS COMPANY (US) | 1977-05-10 | — | — | US | disclosed |