Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | CFD | P00746 | 3/20 | 0.37 |
| ▸ | F11 | P03951 | 2/20 | 0.37 |
| ▸ | TPSB2 | P20231 | 2/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11704655 | 0.88 | PTGS1 (0.46) | GLASTING1KDM4ETDP1MAPT | |
| SCHEMBL11549030 | 0.86 | GLA (0.48) | GLASTING1KDM4ETDP1MAPT | |
| SCHEMBL11705739 | 0.80 | GLA (0.53) | GLASTING1KDM4ETDP1MAPT | |
| SCHEMBL11562028 | 0.78 | TDP1 (0.47) | GLASTING1KDM4ETDP1CYP2D6 | |
| SCHEMBL11706504 | 0.78 | TDP1 (0.47) | GLASTING1KDM4ETDP1SMN1; SMN2 | |
| SCHEMBL11560079 | 0.78 | TDP1 (0.47) | GLASTING1KDM4ETDP1CYP2D6 | |
| SCHEMBL11554914 | 0.76 | GLA (0.43) | GLASTING1KDM4ETDP1CYP2D6 | |
| Methylamine SCHEMBL10761577 | 0.76 | GLA (0.44) | GLASTING1KDM4ETDP1CYP2D6 | |
| SCHEMBL20763280 | 0.73 | STING1 (0.72) | GLASTING1KDM4EMEN1KMT2A | |
| SCHEMBL9550449 | 0.72 | GLA (0.56) | GLASTING1KDM4ETDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4013692-A | ANTIINFLAMMATORY, ANTIPYRETICS, ANALGESICS | RIKER LABORATORIES, INC. (US) | 1977-03-22 | — | — | US | claimed |
| US-4013692-A | ANTIINFLAMMATORY, ANTIPYRETICS, ANALGESICS | RIKER LABORATORIES, INC. (US) | 1977-03-22 | — | — | US | disclosed |