Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28557239 | 0.83 | — | — | |
| SCHEMBL7876118 | 0.81 | MAPK1 (0.33) | MAPK1TSHRTDP1ALDH1A1 | |
| SCHEMBL8820911 | 0.79 | — | — | |
| SCHEMBL19973310 | 0.79 | — | — | |
| SCHEMBL14561038 | 0.79 | TSHR (0.31) | TSHR | |
| SCHEMBL134615 | 0.78 | TSHR (0.36) | TSHRTDP1 | |
| SCHEMBL15151374 | 0.78 | MAPK1 (0.35) | MAPK1TSHRTDP1ALDH1A1CYP1A2 | |
| SCHEMBL4577969 | 0.78 | MAPK1 (0.35) | MAPK1TSHRTDP1ALDH1A1CYP1A2 | |
| SCHEMBL3801500 | 0.77 | MAPK1 (0.31) | MAPK1 | |
| SCHEMBL9585530 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4002647-A | INSECTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1977-01-11 | — | — | US | disclosed |