Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.51 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11711190 | 0.92 | POLB (0.72) | POLBKDM4EALDH1A1ADORA2ANUDT1 | |
| SCHEMBL11710086 | 0.86 | POLB (0.76) | POLBKDM4EALDH1A1KLK7GAA | |
| SCHEMBL11704782 | 0.80 | SMN1; SMN2 (0.56) | POLBALDH1A1NUDT1GAAMAPT | |
| SCHEMBL11706420 | 0.77 | MAPT (0.79) | POLBKDM4EALDH1A1ADORA2ANUDT1 | |
| SCHEMBL11710848 | 0.77 | POLB (1.00) | POLBKDM4EALDH1A1GAAMAPT | |
| SCHEMBL11705840 | 0.77 | POLB (0.74) | POLBKDM4EALDH1A1KLK7GAA | |
| SCHEMBL1621897 | 0.76 | NPC1 (0.53) | POLBKDM4EALDH1A1GAAMAPT | |
| SCHEMBL11707368 | 0.75 | POLB (0.71) | POLBKDM4EALDH1A1KLK7GAA | |
| SCHEMBL6701729 | 0.75 | ADORA2A (0.57) | POLBKDM4EALDH1A1ADORA2ANUDT1 | |
| SCHEMBL11705225 | 0.74 | POLB (0.57) | POLBKDM4EALDH1A1NUDT1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4002755-A | Triazoloquinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-01-11 | — | — | US | disclosed |