SCHEMBL11708139

SCHEMBL11708139

C=CCN1CCN/C1=C\[N+](=O)[O-]

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.51
CHRNA1 P02708 1/20 0.45
CHRNA3 P32297 1/20 0.45
CHRNA7 P36544 1/20 0.45
ALDH1A1 P00352 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7999137 1.00 SMN1; SMN2 (0.51) SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1
SCHEMBL7999133 1.00 SMN1; SMN2 (0.51) SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1
SCHEMBL11710973 0.90 CHRNA1 (0.52) SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1
SCHEMBL11811499 0.90 CHRNA1 (0.52) SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1
SCHEMBL11708466 0.89 CHRNA1 (0.48) SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1
SCHEMBL11805897 0.89 CHRNA1 (0.48) SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1
SCHEMBL11810271 0.85 SMN1; SMN2 (0.52) SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1
SCHEMBL11709538 0.85 SMN1; SMN2 (0.52) SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1
SCHEMBL11811450 0.84 SMN1; SMN2 (0.55) SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1
SCHEMBL11812512 0.84 SMN1; SMN2 (0.55) SMN1; SMN2CHRNA1CHRNA3CHRNA7ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4029791-A INSECTICIDES SHELL OIL COMPANY (US) 1977-06-14 US disclosed
US-4002765-A 2-(Nitromethylene)-1,3-diazacycloalkane insect control agents SHELL OIL COMPANY (US) 1977-01-11 US disclosed
US-3971774-A INSECTICIDE SHELL OIL COMPANY (US) 1976-07-27 US disclosed
US-3969354-A INSECTICIDE SHELL OIL COMPANY (US) 1976-07-13 US disclosed
US-3948934-A 2-(Nitromethylene)-1,3-diazacycloalkane insect control agents SHELL OIL COMPANY (US) 1976-04-06 US disclosed