SCHEMBL11708641

SCHEMBL11708641

CCCCCCc1ccc2c(c1CCCCCC)C(=O)OC2=O

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ELANE P08246 5/20 0.45
CTSG P08311 3/20 0.45
NR1H2 P55055 1/20 0.41
NR1H3 Q13133 1/20 0.41
CYP1A1 P04798 1/20 0.40
TYR P14679 1/20 0.40
LIPG Q9Y5X9 1/20 0.38
CDC25A P30304 5/20 0.38
CDC25B P30305 5/20 0.38
CDC25C P30307 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11872826 0.88 ELANE (0.45) ELANECTSGNR1H2NR1H3CYP1A1
SCHEMBL27455391 0.86 CYP1A1 (0.40) ELANECTSGNR1H2NR1H3CYP1A1
SCHEMBL19950622 0.84 ELANE (0.40) ELANECTSG
SCHEMBL28740970 0.84 ELANE (0.60) ELANECTSGTYR
SCHEMBL8923246 0.81 NR1H2 (0.50) ELANECTSGNR1H2NR1H3LIPG
SCHEMBL8920831 0.81 NR1H2 (0.50) ELANECTSGNR1H2NR1H3LIPG
SCHEMBL8340233 0.81 NR1H2 (0.50) ELANECTSGNR1H2NR1H3LIPG
SCHEMBL8344455 0.81 NR1H2 (0.50) ELANECTSGNR1H2NR1H3LIPG
SCHEMBL8920919 0.81 NR1H2 (0.50) ELANECTSGNR1H2NR1H3LIPG
SCHEMBL1425746 0.81 NR1H2 (0.50) ELANECTSGNR1H2NR1H3LIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4016174-A USED IN PRESSURE SENSITIVE RECORD MATERIALS AND MANIFOLD MARKING SYSTEMS NCR CORPORATION (US) 1977-04-05 US disclosed