Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.70 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL1170002 | 1.00 | CA4 (0.70) | CA4FAHD1MEN1LDHABLM | |
| Oxalic Acid SCHEMBL28652536 | 0.95 | CA4 (0.64) | CA4FAHD1MEN1LDHABLM | |
| Oxalic Acid SCHEMBL28334564 | 0.95 | CA4 (0.64) | CA4FAHD1MEN1LDHABLM | |
| Oxalic Acid SCHEMBL25179700 | 0.94 | CA4 (0.78) | CA4FAHD1MEN1LDHABLM | |
| Oxalic Acid SCHEMBL31182112 | 0.94 | — | — | |
| Oxalic Acid SCHEMBL28833584 | 0.94 | — | — | |
| Oxalic Acid SCHEMBL93229 | 0.94 | CA4 (0.78) | CA4FAHD1MEN1LDHABLM | |
| Oxalic Acid SCHEMBL21753837 | 0.94 | CA4 (0.78) | CA4FAHD1MEN1LDHABLM | |
| Oxalic Acid SCHEMBL79869 | 0.94 | CA4 (0.78) | CA4FAHD1MEN1LDHABLM | |
| Oxalic Acid SCHEMBL43709 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2281547-B1 | Tooth sensitivity treatment compositions | JOHNSON & JOHNSON CONSUMER INC (US) | 2018-01-03 | — | — | EP | claimed |
| US-9060947-B2 | Tooth sensitivity treatment compositions | MCNEIL-PPC, INC. (US) | 2015-06-23 | — | — | US | claimed |
| US-8632754-B2 | Tooth sensitivity treatment compositions | MCNEIL-PPC, INC. (US) | 2014-01-21 | — | — | US | claimed |
| EP-2281546-A2 | Tooth sensitivity treatment compositions | McNeil-PPC, Inc. (US) | 2011-02-09 | — | — | EP | claimed |
| EP-2281547-A2 | Tooth sensitivity treatment compositions | McNeil-PPC, Inc. (US) | 2011-02-09 | — | — | EP | claimed |
| US-20110027197-A1 | TOOTH SENSITIVITY TREATMENT COMPOSITIONS | MCNEIL-PPC, INC. (US) | 2011-02-03 | — | — | US | claimed |
| US-20110027196-A1 | TOOTH SENSITIVITY TREATMENT COMPOSITIONS | MCNEIL-PPC, INC. (US) | 2011-02-03 | — | — | US | claimed |
| EP-2281546-B1 | Tooth sensitivity treatment compositions | JOHNSON & JOHNSON CONSUMER INC (US) | 2018-09-19 | — | — | EP | disclosed |
| EP-2281548-B1 | Tooth sensitivity treatment compositions | JOHNSON & JOHNSON CONSUMER INC (US) | 2018-01-31 | — | — | EP | disclosed |
| EP-2281547-B1 | Tooth sensitivity treatment compositions | JOHNSON & JOHNSON CONSUMER INC (US) | 2018-01-03 | — | — | EP | disclosed |
| US-9060947-B2 | Tooth sensitivity treatment compositions | MCNEIL-PPC, INC. (US) | 2015-06-23 | — | — | US | disclosed |
| US-8632754-B2 | Tooth sensitivity treatment compositions | MCNEIL-PPC, INC. (US) | 2014-01-21 | — | — | US | disclosed |
| US-8603442-B2 | Tooth sensitivity treatment compositions | MCNEIL-PPC, INC. (US) | 2013-12-10 | — | — | US | disclosed |
| EP-2281546-A2 | Tooth sensitivity treatment compositions | McNeil-PPC, Inc. (US) | 2011-02-09 | — | — | EP | disclosed |
| EP-2281548-A2 | Tooth sensitivity treatment compositions | McNeil-PPC, Inc. (US) | 2011-02-09 | — | — | EP | disclosed |
| EP-2281547-A2 | Tooth sensitivity treatment compositions | McNeil-PPC, Inc. (US) | 2011-02-09 | — | — | EP | disclosed |
| US-20110027197-A1 | TOOTH SENSITIVITY TREATMENT COMPOSITIONS | MCNEIL-PPC, INC. (US) | 2011-02-03 | — | — | US | disclosed |
| US-20110027196-A1 | TOOTH SENSITIVITY TREATMENT COMPOSITIONS | MCNEIL-PPC, INC. (US) | 2011-02-03 | — | — | US | disclosed |
| US-20110027198-A1 | TOOTH SENSITIVITY TREATMENT COMPOSITIONS | MCNEIL-PPC, INC. (US) | 2011-02-03 | — | — | US | disclosed |