Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11709328 | 1.00 | EPHX1 (0.47) | EPHX1KMT2ANPSR1HPGDEPHX2 | |
| SCHEMBL8464549 | 0.93 | KMT2A (0.53) | EPHX1KMT2ANPSR1EPHX2NPC1 | |
| SCHEMBL13647683 | 0.86 | KMT2A (0.47) | EPHX1KMT2ANPSR1NPC1RAB9A | |
| SCHEMBL25657958 | 0.86 | KMT2A (0.47) | EPHX1KMT2ANPSR1NPC1MAPT | |
| SCHEMBL15112953 | 0.86 | KMT2A (0.47) | EPHX1KMT2ANPSR1MAPTSMN1; SMN2 | |
| SCHEMBL13715458 | 0.83 | EPHX1 (0.55) | EPHX1KMT2AHPGD | |
| SCHEMBL19426065 | 0.82 | EPHX1 (0.63) | EPHX1KMT2ANPSR1EPHX2NPC1 | |
| SCHEMBL1067515 | 0.82 | EPHX1 (0.63) | EPHX1KMT2ANPSR1EPHX2NPC1 | |
| SCHEMBL8393998 | 0.82 | EPHX1 (0.63) | EPHX1KMT2ANPSR1EPHX2NPC1 | |
| SCHEMBL15700754 | 0.82 | EPHX1 (0.63) | EPHX1KMT2ANPSR1EPHX2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532187-B1 | WATER-DILUTABLE POLYESTERS WITH A CYCLIC IMIDE AND ISOCYANURATE STRUCTURE | BAYER MATERIALSCIENCE AG (DE) | 2009-10-14 | — | — | EP | disclosed |
| US-4015015-A | Chemical fire alarm | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-03-29 | — | — | US | disclosed |