Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26756027 | 1.00 | MAPT (0.42) | MAPTCHRM2ALDH1A1CA12CA2 | |
| SCHEMBL15287 | 0.97 | MAPT (0.44) | MAPTCHRM2ALDH1A1CA12CA2 | |
| SCHEMBL7108954 | 0.93 | CA12 (0.44) | MAPTCHRM2ALDH1A1CA12CA2 | |
| SCHEMBL2978725 | 0.91 | MAPT (0.50) | MAPTCHRM2ALDH1A1CA12CA2 | |
| SCHEMBL3428918 | 0.90 | — | — | |
| SCHEMBL16105559 | 0.90 | CHRM2 (0.46) | MAPTCHRM2ALDH1A1CA12CA2 | |
| SCHEMBL26756024 | 0.90 | CHRM2 (0.52) | MAPTCHRM2ALDH1A1CA12CA2 | |
| SCHEMBL24631447 | 0.89 | KDM5A (0.37) | MAPTCHRM2ALDH1A1CA12CA2 | |
| SCHEMBL26493909 | 0.88 | CHRM2 (0.50) | MAPTCHRM2ALDH1A1LSSSMN1; SMN2 | |
| SCHEMBL26493928 | 0.88 | CHRM2 (0.50) | MAPTCHRM2ALDH1A1LSSSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4048322-A | Bronchially effective xanthene-9-carboxylates | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1977-09-13 | — | — | US | disclosed |
| US-4044146-A | CHOLINOLYTIC, BRONCHOSPASMOLYTIC | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1977-08-23 | — | — | US | disclosed |