Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11715589 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2TAS1R3TAS1R1TAS1R2MAPT | |
| SCHEMBL2886489 | 0.86 | HSD17B10 (0.55) | SMN1; SMN2MAPTHPGDMAPK1KMT2A | |
| SCHEMBL2886492 | 0.86 | HSD17B10 (0.55) | SMN1; SMN2MAPTHPGDMAPK1KMT2A | |
| SCHEMBL5404380 | 0.84 | MAPT (0.46) | SMN1; SMN2MAPTHPGDMAPK1KMT2A | |
| SCHEMBL5404383 | 0.84 | MAPT (0.46) | SMN1; SMN2MAPTHPGDMAPK1KMT2A | |
| SCHEMBL1974848 | 0.83 | MAPT (0.51) | SMN1; SMN2MAPTHPGDMAPK1KMT2A | |
| SCHEMBL1717226 | 0.83 | MAPT (0.51) | SMN1; SMN2MAPTHPGDMAPK1KMT2A | |
| SCHEMBL1717228 | 0.83 | MAPT (0.51) | SMN1; SMN2MAPTHPGDMAPK1KMT2A | |
| SCHEMBL11723450 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTMAPK1KMT2AALDH1A1 | |
| SCHEMBL11723465 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTMAPK1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4027037-A | ARTHROPOD METAMORPHOSIS INHIBITORS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-31 | — | — | US | disclosed |