Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 5/20 | 0.42 |
| ▸ | HMGCR | P04035 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | F13A1 | P00488 | 3/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11649390 | 0.95 | PTPN7 (0.38) | PTPN7HMGCRRECQLTDP1MAPT | |
| SCHEMBL11769902 | 0.89 | IMPDH1 (0.36) | IMPDH1 | |
| SCHEMBL11720090 | 0.83 | TSHR (0.36) | ALDH1A1LMNA | |
| SCHEMBL11724953 | 0.79 | TSHR (0.37) | MAPTALDH1A1IMPDH1 | |
| SCHEMBL10343438 | 0.76 | F13A1 (0.53) | MAPTTBXAS1F13A1LMNA | |
| SCHEMBL11129257 | 0.76 | F13A1 (0.53) | MAPTTBXAS1F13A1LMNA | |
| SCHEMBL11111664 | 0.76 | F13A1 (0.53) | MAPTTBXAS1F13A1LMNA | |
| SCHEMBL11106275 | 0.76 | F13A1 (0.53) | MAPTTBXAS1F13A1LMNA | |
| SCHEMBL11722979 | 0.75 | GSTP1 (0.35) | MAPTALDH1A1KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL21682850 | 0.71 | PTPN7 (0.74) | PTPN7HMGCRRECQLTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4054741-A | Derivatives of prostanoic acid | AYERST MCKENNA & HARRISON LTD. (CA) | 1977-10-18 | — | — | US | disclosed |