Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 6/20 | 0.89 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.89 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.89 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.89 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.89 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.89 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.89 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.89 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.89 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | APEX1 | P27695 | 2/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11721410 | 1.00 | CHRM2 (0.89) | CHRM2CHRM5CHRM1CHRM3CHRM4 | |
| SCHEMBL11726121 | 0.98 | CHRM2 (0.93) | CHRM2CHRM5CHRM1CHRM3CHRM4 | |
| SCHEMBL11724836 | 0.96 | CHRM2 (0.96) | CHRM2CHRM5CHRM1CHRM3CHRM4 | |
| SCHEMBL11726410 | 0.96 | CHRM2 (0.96) | CHRM2CHRM5CHRM1CHRM3CHRM4 | |
| SCHEMBL11725498 | 0.96 | CHRM2 (0.96) | CHRM2CHRM5CHRM1CHRM3CHRM4 | |
| SCHEMBL11730865 | 0.96 | CHRM2 (0.96) | CHRM2CHRM5CHRM1CHRM3CHRM4 | |
| Oxotremorine SCHEMBL2128 | 0.94 | CHRM2 (1.00) | CHRM2CHRM5CHRM1CHRM3CHRM4 | |
| Oxotremorine SCHEMBL10532590 | 0.93 | CHRM2 (0.96) | CHRM2CHRM5CHRM1CHRM3CHRM4 | |
| SCHEMBL31263727 | 0.91 | CHRM2 (0.93) | CHRM2CHRM5CHRM1CHRM3CHRM4 | |
| Oxotremorine SCHEMBL1320883 | 0.89 | CHRM2 (0.90) | CHRM2CHRM5CHRM1CHRM3CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065471-A | N-(4-Amino-2-butynyl)imides | STERLING DRUG INC. (US) | 1977-12-27 | — | — | US | disclosed |