Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.69 |
| ▸ | GFER | P55789 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | STAT3 | P40763 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.62 |
| ▸ | APP | P05067 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11812563 | 0.94 | RAD52 (0.64) | RAD52GFERMAPTSMN1; SMN2MEN1 | |
| SCHEMBL28845646 | 0.90 | RAD52 (0.56) | RAD52GFERMAPTSMN1; SMN2MEN1 | |
| SCHEMBL11726280 | 0.88 | MAPKAPK2 (0.75) | RAD52GFERMAPTSMN1; SMN2MEN1 | |
| SCHEMBL10838774 | 0.88 | MAPKAPK2 (0.61) | RAD52GFERMAPTSMN1; SMN2MEN1 | |
| SCHEMBL11546047 | 0.87 | MAPT (0.59) | RAD52GFERMAPTSMN1; SMN2MEN1 | |
| SCHEMBL11542671 | 0.87 | SMN1; SMN2 (0.58) | RAD52GFERMAPTSMN1; SMN2MEN1 | |
| SCHEMBL11541585 | 0.87 | MAPT (0.58) | RAD52GFERMAPTSMN1; SMN2MEN1 | |
| SCHEMBL11734043 | 0.86 | RAD52 (0.57) | RAD52GFERMAPTSMN1; SMN2MEN1 | |
| SCHEMBL11542429 | 0.86 | MAPT (0.57) | RAD52GFERMAPTSMN1; SMN2MEN1 | |
| SCHEMBL11542920 | 0.86 | MAPT (0.57) | RAD52GFERMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4057633-A | ANTIANXIETY, HYPOTENSIVE | THE UPJOHN COMPANY (US) | 1977-11-08 | — | — | US | disclosed |
| US-3992382-A | HYPERTENSION AND ANXIETY TREATMENT | THE UPJOHN COMPANY (US) | 1976-11-16 | — | — | US | disclosed |