⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28725750 | 0.68 | — | — | |
| SCHEMBL403252 | 0.68 | — | — | |
| SCHEMBL1463989 | 0.66 | — | — | |
| SCHEMBL7969014 | 0.64 | — | — | |
| SCHEMBL8088294 | 0.64 | — | — | |
| SCHEMBL28476813 | 0.62 | — | — | |
| SCHEMBL290421 | 0.59 | — | — | |
| SCHEMBL8082785 | 0.58 | — | — | |
| SCHEMBL28918027 | 0.56 | — | — | |
| SCHEMBL29708474 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110402248-B | Azaindoles as HPK1 inhibitors | 豪夫迈·罗氏有限公司 | 2023-01-06 | — | — | CN | disclosed |
| US-4009168-A | STABILIZERS FOR POLYOLEFINS | UBE INDUSTRIES, LTD. (JA) | 1977-02-22 | — | — | US | disclosed |