Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1173838 | 0.83 | BACE1 (0.65) | BACE1APP | |
| SCHEMBL2582229 | 0.78 | BACE1 (0.66) | BACE1APP | |
| SCHEMBL6936794 | 0.78 | BACE1 (0.62) | BACE1APP | |
| SCHEMBL363040 | 0.78 | BACE1 (1.00) | BACE1APP | |
| SCHEMBL362993 | 0.78 | BACE1 (1.00) | BACE1APP | |
| SCHEMBL360942 | 0.78 | BACE1 (1.00) | BACE1APP | |
| SCHEMBL1910516 | 0.77 | BACE1 (0.65) | BACE1APP | |
| SCHEMBL362824 | 0.77 | BACE1 (1.00) | BACE1APP | |
| SCHEMBL361087 | 0.77 | BACE1 (1.00) | BACE1APP | |
| SCHEMBL568075 | 0.77 | BACE1 (0.61) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110046122-A1 | 3-AMINO-5-PHENYL-5,6-DIHYDRO-2H-[1,4]OXAZINES | SIENA BIOTECH S.P.A. (IT) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046122-A1 | 3-AMINO-5-PHENYL-5,6-DIHYDRO-2H-[1,4]OXAZINES | BACE2, BACE1, APP | BACE1 2/4885APP 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.