Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAT1 | P18440 | 1/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.60 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | PIM1 | P11309 | 2/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | CDC7 | O00311 | 1/20 | 0.53 |
| ▸ | PLK4 | O00444 | 1/20 | 0.53 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.53 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.53 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.53 |
| ▸ | PRKCG | P05129 | 1/20 | 0.53 |
| ▸ | CDK1 | P06493 | 1/20 | 0.53 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.53 |
| ▸ | AKT1 | P31749 | 1/20 | 0.53 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.53 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11729145 | 1.00 | NAT1 (0.60) | NAT1PDE4BCISD1PDE3AMAOB | |
| SCHEMBL13499563 | 0.87 | NAT1 (0.72) | NAT1PDE4BCISD1PDE3AMAOB | |
| SCHEMBL18102948 | 0.84 | NAT1 (0.64) | NAT1PDE4BCISD1PDE3AMAOB | |
| SCHEMBL11738418 | 0.82 | NAT1 (0.73) | NAT1PDE4BCISD1PDE3AMAOB | |
| SCHEMBL11738412 | 0.82 | NAT1 (0.73) | NAT1PDE4BCISD1PDE3AMAOB | |
| SCHEMBL13499574 | 0.81 | NAT1 (0.64) | NAT1PDE4BCISD1PDE3AMAOB | |
| SCHEMBL2065192 | 0.78 | CISD1 (0.70) | NAT1PDE4BCISD1PTP4A3MEN1 | |
| SCHEMBL2065191 | 0.78 | CISD1 (0.70) | NAT1PDE4BCISD1PTP4A3MEN1 | |
| SCHEMBL10090195 | 0.78 | CISD1 (0.70) | NAT1PDE4BCISD1PTP4A3MEN1 | |
| SCHEMBL15347653 | 0.77 | NAT1 (0.76) | NAT1PDE4BCISD1PDE3AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4018891-A | INHIBITORS OF ANTIGEN-ANTIBODY REACTIONS | RICHARDSON-MERRELL INC. (US) | 1977-04-19 | — | — | US | disclosed |
| US-3960892-A | ANTIGEN-ANTIBODY REACTION INHIBITION | RICHARDSON-MERRELL INC. (US) | 1976-06-01 | — | — | US | disclosed |