Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11730729 | 0.80 | TSHR (0.31) | TSHR | |
| SCHEMBL11727365 | 0.79 | TSHR (0.33) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL4379120 | 0.78 | TSHR (0.36) | TSHRLMNAHSD17B10MGAMGAA | |
| SCHEMBL4373441 | 0.76 | TSHR (0.37) | TSHRLMNAHSD17B10MGAMGAA | |
| SCHEMBL11307490 | 0.76 | TSHR (0.37) | TSHRLMNAHSD17B10MGAMGAA | |
| SCHEMBL11656664 | 0.74 | TSHR (0.36) | TSHRLMNAHSD17B10MGAMGAA | |
| SCHEMBL5248290 | 0.73 | TSHR (0.34) | TSHRHSD17B10MGAMGAASI | |
| Hydrochloric Acid SCHEMBL11658513 | 0.73 | KDM4E (0.38) | TSHRLMNAHSD17B10MGAMGAA | |
| SCHEMBL8892122 | 0.73 | — | — | |
| SCHEMBL17694763 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4022794-A | VASODILATION | MERCK & CO., INC. (US) | 1977-05-10 | — | — | US | disclosed |