Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11737464 | 0.99 | — | — | |
| SCHEMBL11737259 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL11743814 | 0.92 | CNR1 (0.40) | — | |
| SCHEMBL11737456 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL11738680 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL11735440 | 0.86 | CNR1 (0.42) | — | |
| Hydrochloric Acid SCHEMBL11356338 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL11739139 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL11742850 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL11545341 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4025630-A | Anesthesia methods using benzopyrans and esters thereof as pre-anesthesia medication | ABBOTT LABORATORIES (US) | 1977-05-24 | — | — | US | disclosed |