Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 13/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGFR | P43088 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11727905 | 1.00 | PTGER2 (0.45) | PTGER2PTGER4PTGER3L3MBTL1PPARG | |
| SCHEMBL11732308 | 1.00 | PTGER2 (0.45) | PTGER2PTGER4PTGER3L3MBTL1PPARG | |
| SCHEMBL11727535 | 0.89 | PTGER4 (0.57) | PTGER2PTGER4PTGER3TBXA2RPTGFR | |
| SCHEMBL5852489 | 0.89 | PTGER4 (0.57) | PTGER2PTGER4PTGER3TBXA2RPTGFR | |
| SCHEMBL11727526 | 0.89 | PTGER4 (0.57) | PTGER2PTGER4PTGER3TBXA2RPTGFR | |
| SCHEMBL11727538 | 0.89 | PTGER4 (0.57) | PTGER2PTGER4PTGER3TBXA2RPTGFR | |
| SCHEMBL11737293 | 0.88 | PTGER2 (0.36) | PTGER2PTGER4PTGER3L3MBTL1PPARG | |
| SCHEMBL11729341 | 0.88 | PTGER2 (0.39) | PTGER2PTGER4PTGER3L3MBTL1PPARG | |
| SCHEMBL11730961 | 0.84 | MAPT (0.39) | PTGER2PTGER4PTGER3L3MBTL1PPARG | |
| SCHEMBL11732351 | 0.83 | PTGER2 (0.37) | PTGER2PTGER4PTGER3TBXA2RPTGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4022794-A | VASODILATION | MERCK & CO., INC. (US) | 1977-05-10 | — | — | US | disclosed |