Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.78 |
| ▸ | BCHE | P06276 | 14/20 | 0.75 |
| ▸ | ACHE | P22303 | 7/20 | 0.75 |
| ▸ | CNR2 | P34972 | 7/20 | 0.75 |
| ▸ | CNR1 | P21554 | 7/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11674118 | 0.96 | APP (0.78) | APPBCHEACHECNR2CNR1 | |
| SCHEMBL11726658 | 0.94 | APP (0.82) | APPBCHEACHECNR2CNR1 | |
| SCHEMBL11672560 | 0.93 | APP (0.91) | APPBCHEACHECNR2CNR1 | |
| SCHEMBL11672632 | 0.93 | APP (0.77) | APPBCHEACHECNR2CNR1 | |
| SCHEMBL11725593 | 0.92 | APP (0.76) | APPBCHEACHECNR2CNR1 | |
| SCHEMBL11734257 | 0.92 | APP (0.76) | APPBCHEACHECNR2CNR1 | |
| SCHEMBL11672542 | 0.91 | APP (0.87) | APPBCHEACHECNR2CNR1 | |
| SCHEMBL11728868 | 0.90 | APP (0.73) | APPBCHEACHECNR2CNR1 | |
| SCHEMBL11729825 | 0.90 | APP (0.73) | APPBCHEACHECNR2CNR1 | |
| SCHEMBL11731490 | 0.90 | APP (0.76) | APPBCHEACHECNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001426-A | HAVING CORONARY VASODILATOR ACTIVITY | SMITHKLINE CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |