Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | KLK1 | P06870 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL407257 | 0.80 | TYR (0.54) | TYRMEN1KMT2AIDO1RAB9A | |
| SCHEMBL31391056 | 0.79 | AKR1C3 (0.64) | AKR1C3AKR1C2HTR2AHTR2CHTR2B | |
| SCHEMBL29955760 | 0.78 | CYP1A2 (0.56) | HTR2AHTR2CHTR2BKMT2ACYP1A2 | |
| SCHEMBL720558 | 0.78 | CYP1A2 (0.56) | HTR2AHTR2CHTR2BKMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL5197217 | 0.78 | TYR (0.52) | TYRMEN1KMT2AIDO1RAB9A | |
| SCHEMBL453825 | 0.77 | TYR (0.44) | TYRMEN1KMT2ATSHRMAPT | |
| SCHEMBL181347 | 0.77 | UGT2B7 (0.58) | AKR1C3AKR1C2TYRUGT2B7MEN1 | |
| SCHEMBL30031337 | 0.77 | UGT2B7 (0.58) | AKR1C3AKR1C2TYRUGT2B7MEN1 | |
| SCHEMBL10309472 | 0.77 | AKR1C3 (0.49) | AKR1C3AKR1C2HTR2AHTR2CHTR2B | |
| SCHEMBL11739548 | 0.76 | CYP1A2 (0.59) | AKR1C3AKR1C2MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4045485-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC AND ANTIPRURITIC ACTIVITY | SYNTEX CORPORATION (US) | 1977-08-30 | — | — | US | disclosed |
| US-3960936-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS, SKIN DISORDERS | SYNTEX CORPORATION (PM) | 1976-06-01 | — | — | US | disclosed |
| US-3947472-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, ANTIPRURITIC | SYNTEX CORPORATION (PM) | 1976-03-30 | — | — | US | disclosed |
| US-3935273-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, ANTIPRURITIC | SYNTEX CORPORATION (US) | 1976-01-27 | — | — | US | disclosed |