Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL315831 | 0.92 | — | — | |
| SCHEMBL9072310 | 0.92 | — | — | |
| SCHEMBL13817429 | 0.92 | — | — | |
| Propylene Glycol SCHEMBL20718784 | 0.87 | TDP1 (0.50) | TDP1TSHRHSD17B10ALDH1A1PIK3CD | |
| Propylene Glycol SCHEMBL2241207 | 0.86 | TDP1 (0.62) | TDP1TSHRHSD17B10ALDH1A1PIK3CD | |
| Propylene Glycol SCHEMBL15509336 | 0.81 | TDP1 (0.56) | TDP1TSHRHSD17B10ALDH1A1PIK3CD | |
| Propylene Glycol SCHEMBL17967765 | 0.81 | TDP1 (0.56) | TDP1TSHRHSD17B10ALDH1A1PIK3CD | |
| Propylene Glycol SCHEMBL6390820 | 0.79 | TDP1 (0.53) | TDP1TSHRHSD17B10ALDH1A1PIK3CD | |
| Propylene Glycol SCHEMBL3193750 | 0.78 | TDP1 (0.59) | TDP1TSHRHSD17B10ALDH1A1 | |
| Propylene Glycol SCHEMBL7219184 | 0.77 | TDP1 (0.50) | TDP1TSHRHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10362786-B2 | Stable aqueous spore-containing formulation | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2019-07-30 | — | — | US | disclosed |
| US-20110033436-A1 | STABLE AQUEOUS SPORE-CONTAINING FORMULATION | BASF CORPORATION | 2011-02-10 | — | — | US | disclosed |