Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | XBP1 | P17861 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11148926 | 0.88 | MEN1 (0.62) | MEN1KMT2AHSP90AA1MAPTMAPK1 | |
| SCHEMBL10796992 | 0.86 | MEN1 (0.48) | MEN1KMT2AHSP90AA1MAPTMAPK1 | |
| SCHEMBL11587093 | 0.86 | MEN1 (0.48) | MEN1KMT2AHSP90AA1MAPTMAPK1 | |
| SCHEMBL11737102 | 0.85 | MAPT (0.51) | MEN1KMT2AHSP90AA1MAPTMAPK1 | |
| SCHEMBL11741755 | 0.83 | MEN1 (0.57) | MEN1KMT2AHSP90AA1MAPTMAPK1 | |
| SCHEMBL11743221 | 0.83 | MEN1 (0.66) | MEN1KMT2AHSP90AA1MAPTMAPK1 | |
| SCHEMBL2681112 | 0.83 | MEN1 (0.57) | MEN1KMT2AHSP90AA1MAPTMAPK1 | |
| SCHEMBL11152920 | 0.83 | MEN1 (0.59) | MEN1KMT2AHSP90AA1MAPTMAPK1 | |
| SCHEMBL11156657 | 0.83 | KMT2A (0.79) | MEN1KMT2AHSP90AA1MAPTMAPK1 | |
| SCHEMBL11745102 | 0.83 | MAPT (0.64) | MEN1KMT2AHSP90AA1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4018896-A | PLANT DISEASES | ELI LILLY AND COMPANY (US) | 1977-04-19 | — | — | US | disclosed |