Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.48 |
| ▸ | MDM4 | O15151 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GALK1 | P51570 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28088781 | 0.81 | MAPT (0.50) | MAPTLMNAMDM2MDM4MMP8 | |
| SCHEMBL9301284 | 0.81 | MAPT (0.50) | MAPTLMNAMDM2MDM4MMP8 | |
| SCHEMBL8680909 | 0.81 | MAPT (0.50) | MAPTLMNAMDM2MDM4MMP8 | |
| SCHEMBL1994994 | 0.80 | ATM (0.48) | MAPTLMNAMDM2MDM4MMP8 | |
| SCHEMBL1994993 | 0.80 | ATM (0.48) | MAPTLMNAMDM2MDM4MMP8 | |
| SCHEMBL8624954 | 0.80 | MAPT (0.49) | MAPTLMNAMDM2MDM4MMP8 | |
| SCHEMBL11607920 | 0.79 | MAPT (0.48) | MAPTLMNAMDM2MDM4MMP8 | |
| Potassium Ion SCHEMBL8624951 | 0.79 | MAPT (0.48) | MAPTLMNAMDM2MDM4MMP8 | |
| Potassium Ion SCHEMBL29349588 | 0.79 | MAPT (0.48) | MAPTLMNAMDM2MDM4MMP8 | |
| SCHEMBL9301307 | 0.79 | MAPT (0.48) | MAPTLMNAMDM2MDM4MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053470-A | BACTERICIDES, ANTIBIOTICS | PARKE, DAVIS & COMPANY (US) | 1977-10-11 | — | — | US | disclosed |
| US-3954734-A | PENICILLIN AND CEPHALOSPORIN TYPE | PARKE, DAVIS & COMPANY | 1976-05-04 | — | — | US | disclosed |