Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.97 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | EYA3 | Q99504 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7504805 | 0.99 | PTPN1 (1.00) | PTPN1MAPTNPC1KMT2ARAB9A | |
| SCHEMBL11672606 | 0.94 | PTPN1 (0.89) | PTPN1MAPTNPC1KMT2ARAB9A | |
| SCHEMBL11732206 | 0.89 | PTPN1 (0.85) | PTPN1MAPTNPC1KMT2ARAB9A | |
| SCHEMBL11673267 | 0.89 | PTPN1 (0.85) | PTPN1MAPTNPC1KMT2ARAB9A | |
| SCHEMBL11729177 | 0.85 | PTPN1 (0.74) | PTPN1MAPTNPC1KMT2ARAB9A | |
| SCHEMBL11732549 | 0.83 | PTPN1 (0.70) | PTPN1MAPTNPC1KMT2ARAB9A | |
| SCHEMBL27716370 | 0.81 | PTPN1 (0.66) | PTPN1MAPTNPC1KMT2ARAB9A | |
| SCHEMBL7507315 | 0.81 | PTPN1 (0.72) | PTPN1MAPTNPC1KMT2ARAB9A | |
| SCHEMBL16581069 | 0.79 | PTPN1 (0.64) | PTPN1MAPTNPC1KMT2ARAB9A | |
| SCHEMBL7596427 | 0.78 | PTPN1 (0.65) | PTPN1MAPTNPC1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001426-A | HAVING CORONARY VASODILATOR ACTIVITY | SMITHKLINE CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |