SCHEMBL117382

SCHEMBL117382

c1ccc(-n2ccnc2)nc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 11/20 0.55
LOXL2 Q9Y4K0 1/20 0.50
ALOX15 P16050 4/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
TSHR P16473 1/20 0.48
IDO1 P14902 1/20 0.48
ACVR1B P36896 1/20 0.48
TGFBR1 P36897 1/20 0.48
CYP2D6 P10635 9/20 0.47
CYP1A2 P05177 8/20 0.47
TDP1 Q9NUW8 7/20 0.47
CYP2C19 P33261 6/20 0.47
ALDH1A1 P00352 4/20 0.47
CYP2C9 P11712 3/20 0.47
MAPK1 P28482 3/20 0.47
HSD17B10 Q99714 3/20 0.47
HPGD P15428 1/20 0.47
HIF1A Q16665 1/20 0.47
LMNA P02545 5/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29401947 1.00 CYP3A4 (0.55) CYP3A4LOXL2ALOX15MEN1KMT2A
Hydrochloric Acid SCHEMBL6446846 0.98 CYP3A4 (0.53) CYP3A4LOXL2ALOX15MEN1KMT2A
Carbamic Acid SCHEMBL7633681 0.88 CYP3A4 (0.49) CYP3A4LOXL2ALOX15MEN1KMT2A
SCHEMBL11570476 0.85 CYP3A4 (0.73) CYP3A4ALOX15MEN1KMT2ATSHR
SCHEMBL20019727 0.84 CYP3A4 (0.44) CYP3A4LOXL2ALOX15MEN1KMT2A
SCHEMBL10066877 0.78 CYP3A4 (0.54) CYP3A4ALOX15MEN1KMT2ATSHR
SCHEMBL1437298 0.78 PLD1 (0.50) CYP3A4MEN1KMT2ATSHRCYP2D6
SCHEMBL30569109 0.78 PLD1 (0.50) CYP3A4MEN1KMT2ATSHRCYP2D6
SCHEMBL28614447 0.77 CYP3A4 (0.52) CYP3A4ALOX15MEN1KMT2ATSHR
Acrolein SCHEMBL6368855 0.77 GAA (0.39) CYP3A4LOXL2ALOX15MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3217 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12534666-B2 Blue phosphorescent material, production method thereof, and photophysical properties thereof KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, SEJONG CAMPUS (KR) 2026-01-27 US claimed
US-12337065-B2 Compositions for treating viral infections and methods for same ACCESS TO ADVANCED HEALTH INSTITUTE (US) 2025-06-24 US claimed
US-12194448-B2 Catalysts for the transformation of carbon dioxide and glycerol to formic acid and lactic acid and methods of making the same THE GEORGE WASHINGTON UNIVERSITY (US) 2025-01-14 US claimed
US-20240124770-A1 COMPOUND, GUEST MATERIAL OF LIGHT-EMITTING LAYER, ORGANIC ELECTROLUMINESCENT DEVICE, AND DISPLAY DEVICE BEIJING NORMAL UNIVERSITY (CN) 2024-04-18 US claimed
CN-116120576-B Preparation method and application of copper transition metal organic framework material 四川轻化工大学 2024-03-12 CN claimed
CN-111727190-B Pyridylimidazole benzodiazepine Zhuo Bingsuan ester compound and synthesis and application thereof 杭州奥默医药股份有限公司 2023-10-27 CN claimed
CN-116730995-A Hydrazide compound, preparation method and application thereof 深圳微芯生物科技股份有限公司 2023-09-12 CN claimed
CN-116288729-A MOF crystal material with water nanotubes, preparation method and application thereof in propylene/propane separation 南京工业大学 2023-06-23 CN claimed
CN-116120576-A Preparation method and application of copper transition metal organic framework material 四川轻化工大学 2023-05-16 CN claimed
US-20230056324-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-02-23 US claimed
EP-0464979-B1 A 1-pyridylimidazole derivative and its production and use SUMITOMO CHEMICAL CO (JP) 1994-08-03 EP claimed
US-5252590-A Insecticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-10-12 US claimed
EP-0520824-A1 1-pyridylimidazole derivatives and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-12-30 EP claimed
US-5122530-A Insecticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-06-16 US claimed
EP-0464979-A1 A 1-pyridylimidazole derivative and its production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-01-08 EP claimed
US-4666683-A WATER INSOLUBLE ION EXCHANGE RESIN ECO-TEC LIMITED (CA) 1987-05-19 US claimed
US-4510151-A HYPOTENSIVE AGENTS USV PHARMACEUTICAL CORPORATION (US) 1985-04-09 US claimed
EP-0051371-B1 IMIDAZOLYLPYRIDINE THERAPEUTIC AGENTS PFIZER INC. (US) 1984-08-29 EP claimed
EP-0051371-A2 Imidazolylpyridine therapeutic agents PFIZER INC. (US) 1982-05-12 EP claimed
US-4302464-A ANTIULCER AGENTS, ANTI-H2-HISTAMINES PFIZER INC. (US) 1981-11-24 US claimed