Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11741679 | 0.79 | CYP1A2 (0.45) | TDP1 | |
| SCHEMBL11744332 | 0.77 | CYP2A6 (0.46) | TDP1ERN1 | |
| SCHEMBL11742279 | 0.76 | CYP2A6 (0.45) | TDP1ERN1 | |
| SCHEMBL29726792 | 0.74 | TP53 (0.50) | TDP1 | |
| SCHEMBL38658983 | 0.74 | TP53 (0.50) | TDP1 | |
| SCHEMBL1780435 | 0.70 | IDO1 (0.54) | — | |
| SCHEMBL2172166 | 0.69 | PIK3CA (0.45) | — | |
| SCHEMBL1876507 | 0.69 | CYP19A1 (0.48) | ERN1 | |
| SCHEMBL11746558 | 0.68 | CYP1A2 (0.46) | ERN1 | |
| SCHEMBL1589868 | 0.68 | ERN1 (0.40) | TDP1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4045485-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC AND ANTIPRURITIC ACTIVITY | SYNTEX CORPORATION (US) | 1977-08-30 | — | — | US | disclosed |
| US-3960936-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS, SKIN DISORDERS | SYNTEX CORPORATION (PM) | 1976-06-01 | — | — | US | disclosed |
| US-3947472-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, ANTIPRURITIC | SYNTEX CORPORATION (PM) | 1976-03-30 | — | — | US | disclosed |
| US-3935273-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC, ANTIPRURITIC | SYNTEX CORPORATION (US) | 1976-01-27 | — | — | US | disclosed |