Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1173864 | 0.93 | NPY2R (1.00) | NPY2RMTTP | |
| SCHEMBL29545438 | 0.93 | NPY2R (1.00) | NPY2RMTTP | |
| SCHEMBL1174048 | 0.93 | NPY2R (1.00) | NPY2RMTTP | |
| SCHEMBL1174691 | 0.93 | NPY2R (1.00) | NPY2RMTTP | |
| Hydrochloric Acid SCHEMBL1174029 | 0.92 | NPY2R (0.98) | NPY2RMTTP | |
| Fumaric Acid SCHEMBL1174738 | 0.90 | NPY2R (0.93) | NPY2RMTTP | |
| Maleic Acid SCHEMBL1174735 | 0.90 | NPY2R (0.93) | NPY2RMTTP | |
| SCHEMBL5127954 | 0.89 | NPY2R (0.80) | NPY2RMTTP | |
| Citric Acid SCHEMBL1174102 | 0.87 | NPY2R (0.88) | NPY2RMTTP | |
| SCHEMBL5084599 | 0.84 | NPY2R (1.00) | NPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338426-B2 | Piperazinyl derivatives useful as modulators of the neuropeptide Y2 receptor | JANSSEN PHARMACEUTICA NV (BE) | 2012-12-25 | — | — | US | disclosed |
| US-20110046151-A1 | PIPERAZINYL DERIVATIVES USEFUL AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR | JANSSEN PHARMACEUTICA NV (BE) | 2011-02-24 | — | — | US | disclosed |
| US-20110046151-A1 | PIPERAZINYL DERIVATIVES USEFUL AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR | JANSSEN PHARMACEUTICA NV (BE) | 2011-02-24 | — | — | US | disclosed |
| WO-2009006185-A1 | PIPERAZINYL DERIVATIVES USEFUL AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046151-A1 | PIPERAZINYL DERIVATIVES USEFUL AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR | NPY2R, NPY1R, NPY5R | NPY2R 1/4885MTTP 2542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.