Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11745227 | 1.00 | CYP19A1 (0.72) | CYP19A1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9264931 | 0.85 | CYP19A1 (0.64) | CYP19A1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9264924 | 0.85 | CYP19A1 (0.64) | CYP19A1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL227066 | 0.85 | TLR9 (0.60) | CYP19A1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28460574 | 0.85 | CYP19A1 (0.76) | CYP19A1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL227065 | 0.85 | TLR9 (0.60) | CYP19A1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL28460573 | 0.85 | CYP19A1 (0.76) | CYP19A1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL15938082 | 0.84 | CYP19A1 (0.51) | CYP19A1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL15938083 | 0.84 | CYP19A1 (0.51) | CYP19A1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11743270 | 0.84 | CYP19A1 (0.51) | CYP19A1MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4013639-A | PREPARATION OF ASYMMETRIC IMINODIBENZYL COMPOUNDS | Kitamura, Eiichi (JA) | 1977-03-22 | — | — | US | disclosed |