Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 1/20 | 0.51 |
| ▸ | CHUK | O15111 | 1/20 | 0.49 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | PRKCG | P05129 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | AKT2 | P31751 | 1/20 | 0.49 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.49 |
| ▸ | BLK | P51451 | 1/20 | 0.49 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.49 |
| ▸ | JAK3 | P52333 | 1/20 | 0.49 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.49 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.49 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11745835 | 1.00 | SMPD1 (0.51) | SMPD1CHUKDAPK3JAK2ROCK2 | |
| SCHEMBL11753814 | 0.85 | KMT2A (0.51) | MEN1KMT2AGAAL3MBTL1HSP90AA1 | |
| SCHEMBL11753810 | 0.85 | KMT2A (0.51) | MEN1KMT2AGAAL3MBTL1HSP90AA1 | |
| SCHEMBL15249764 | 0.83 | PPARG (0.51) | CHUKDAPK3JAK2ROCK2PRKCG | |
| SCHEMBL28477113 | 0.83 | PPARG (0.51) | CHUKDAPK3JAK2ROCK2PRKCG | |
| SCHEMBL28482952 | 0.83 | PPARG (0.51) | CHUKDAPK3JAK2ROCK2PRKCG | |
| SCHEMBL29240439 | 0.83 | PPARG (0.51) | CHUKDAPK3JAK2ROCK2PRKCG | |
| SCHEMBL11748717 | 0.83 | CHUK (0.49) | CHUKDAPK3JAK2ROCK2PRKCG | |
| SCHEMBL29032672 | 0.83 | PPARG (0.51) | CHUKDAPK3JAK2ROCK2PRKCG | |
| SCHEMBL11748722 | 0.83 | CHUK (0.49) | CHUKDAPK3JAK2ROCK2PRKCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4035423-A | Process for the preparation of 3,4-dialkoxyanilines | CIBA-GEIGY CORPORATION (US) | 1977-07-12 | — | — | US | disclosed |