Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA4 | P22748 | 4/20 | 0.44 |
| ▸ | CA6 | P23280 | 4/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8159406 | 0.98 | NPC1 (0.55) | NPC1RAB9AGAAKDM4ESMN1; SMN2 | |
| SCHEMBL11763977 | 0.93 | NPC1 (0.54) | NPC1RAB9AGAAKDM4ESMN1; SMN2 | |
| SCHEMBL8829497 | 0.84 | NPC1 (0.48) | NPC1RAB9AGAAKDM4ESMN1; SMN2 | |
| SCHEMBL10925578 | 0.83 | KDM4E (0.55) | NPC1RAB9AGAAKDM4ESMN1; SMN2 | |
| SCHEMBL6730172 | 0.83 | CA1 (0.47) | NPC1RAB9AGAAKDM4ESMN1; SMN2 | |
| SCHEMBL10504390 | 0.83 | CA1 (0.47) | NPC1RAB9AGAAKDM4ESMN1; SMN2 | |
| SCHEMBL11765051 | 0.83 | NPC1 (0.47) | NPC1RAB9AGAAKDM4ESMN1; SMN2 | |
| SCHEMBL6036885 | 0.83 | NPC1 (0.56) | NPC1RAB9AGAAKDM4ESMN1; SMN2 | |
| Methoxymethane SCHEMBL29852076 | 0.82 | KDM4E (0.57) | NPC1RAB9AGAAKDM4ESMN1; SMN2 | |
| SCHEMBL29852107 | 0.82 | NPC1 (0.49) | NPC1RAB9AGAAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4005107-A | 13-Oxabicyclo(10,4,0)hexadec-1(12)-en-14-one | DAICEL, LTD. (JA) | 1977-01-25 | — | — | US | disclosed |