SCHEMBL1174716

SCHEMBL1174716

C=C(C)C(=O)NCCCCCCCCCCS(=O)(=O)O

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.47
KDM4E B2RXH2 1/20 0.43
MAPK1 P28482 1/20 0.43
HIF1A Q16665 1/20 0.43
PAOX Q6QHF9 2/20 0.37
ADRA1A P35348 1/20 0.36
EPHX1 P07099 5/20 0.35
APP P05067 1/20 0.34
TGFBR1 P36897 1/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34
PLA2G2A P14555 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3447225 1.00 EPHX2 (0.47) EPHX2KDM4EMAPK1HIF1APAOX
SCHEMBL11696279 1.00 EPHX2 (0.47) EPHX2KDM4EMAPK1HIF1APAOX
SCHEMBL3446603 1.00 EPHX2 (0.47) EPHX2KDM4EMAPK1HIF1APAOX
SCHEMBL11697545 1.00 EPHX2 (0.47) EPHX2KDM4EMAPK1HIF1APAOX
SCHEMBL720349 0.98 EPHX2 (0.45) EPHX2KDM4EMAPK1HIF1APAOX
SCHEMBL93530 0.94 EPHX2 (0.41) EPHX2KDM4EMAPK1HIF1APAOX
Ammonia Solution, Strong SCHEMBL18139994 0.93 EPHX2 (0.41) EPHX2KDM4EMAPK1HIF1APAOX
SCHEMBL28542048 0.93 EPHX2 (0.41) EPHX2KDM4EMAPK1HIF1APAOX
SCHEMBL28553716 0.93 EPHX2 (0.41) EPHX2KDM4EMAPK1HIF1APAOX
SCHEMBL28544524 0.93 EPHX2 (0.41) EPHX2KDM4EMAPK1HIF1APAOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6512068-B1 Substantially transparent adhesive composition for hard tissue, and a method for producing it; the adhesive composition exhibits good adhesiveness to hard tissue, especially to both enamel and dentin, and has the advantage of KURARAY CO., LTD. (JP) 2003-01-28 US claimed
WO-2017017155-A1 DENTAL ADHESIVE DENTSPLY DETREY GMBH (DE) 2017-02-02 WO disclosed
US-8389598-B2 Dental polymerizable composition and kit therefor SUN MEDICAL CO., LTD. (JP) 2013-03-05 US disclosed
US-20110028589-A1 DENTAL POLYMERIZABLE COMPOSITION AND KIT THEREFOR SUN MEDICAL CO., LTD. (JP) 2011-02-03 US disclosed
US-7815434-B2 Dental coating kit KURARAY MEDICAL INC. (JP) 2010-10-19 US disclosed
EP-2189147-A1 DENTAL POLYMERIZABLE COMPOSITION AND KIT THEREFOR SUN MEDICAL CO., LTD. (JP) 2010-05-26 EP disclosed
EP-1550428-B1 DENTAL COATING KIT KURARAY MEDICAL INC (JP) 2009-03-18 EP disclosed
EP-1057468-B1 Adhesive composition and method for producing it KURARAY CO (JP) 2006-07-19 EP disclosed
US-20060078510-A1 Dental coating kit KURARAY MEDICAL INC. (JP) 2006-04-13 US disclosed
EP-1550428-A1 DENTAL COATING KIT Kuraray Medical Inc. (JP) 2005-07-06 EP disclosed
US-6512068-B1 Substantially transparent adhesive composition for hard tissue, and a method for producing it; the adhesive composition exhibits good adhesiveness to hard tissue, especially to both enamel and dentin, and has the advantage of KURARAY CO., LTD. (JP) 2003-01-28 US disclosed
EP-1057468-A1 Adhesive composition and method for producing it KURARAY CO., LTD. (JP) 2000-12-06 EP disclosed