SCHEMBL1174728

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1174784	0.88	CKS1B (0.49)	CKS1BSKP1SKP2CNR2GAA
	SCHEMBL15247964	0.86	CKS1B (0.48)	CKS1BSKP1SKP2CNR2GAA
	SCHEMBL12866909	0.84	ADORA1 (0.42)	CKS1BSKP1SKP2GAACYBB
	SCHEMBL4122313	0.83	DPP4 (0.39)	CKS1BSKP1SKP2GAACYBB
	SCHEMBL1174520	0.83	NR1H2 (0.54)	CKS1BSKP1SKP2CNR2ALDH1A1
	SCHEMBL1174694	0.83	CNR2 (0.57)	CNR2GABRG2GABRB3GABRA5GAA
	SCHEMBL1173978	0.82	CKS1B (0.49)	CKS1BSKP1SKP2CNR2
	SCHEMBL1176005	0.81	CKS1B (0.45)	CKS1BSKP1SKP2GAA
	SCHEMBL13867707	0.81	CKS1B (0.48)	CKS1BSKP1SKP2CNR2
	SCHEMBL1173988	0.80	CNR2 (0.60)	CKS1BSKP1SKP2CNR2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.