Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ADAMTS5 | Q9UNA0 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11749979 | 0.94 | CHRM2 (0.51) | GAAMGAMSIMGAM2MAPT | |
| SCHEMBL11751065 | 0.86 | MAPT (0.46) | MAPTLMNAMEN1KMT2AXBP1 | |
| SCHEMBL5483660 | 0.82 | MAPT (0.70) | GAAMGAMSIMGAM2MAPT | |
| SCHEMBL11748423 | 0.81 | MAPT (0.45) | GAAMGAMSIMGAM2MAPT | |
| SCHEMBL5481309 | 0.81 | CHRM2 (0.62) | GAAMGAMSIMGAM2MAPT | |
| SCHEMBL11753047 | 0.80 | CHRM2 (0.51) | MAPTLMNAMEN1KMT2AXBP1 | |
| SCHEMBL11749977 | 0.77 | CHRM2 (0.48) | GAAMGAMSIMGAM2MAPT | |
| SCHEMBL11748640 | 0.73 | CHRM2 (0.78) | GAAMGAMSIMGAM2MAPT | |
| SCHEMBL11748297 | 0.72 | MAPT (0.88) | GAAMGAMSIMGAM2MAPT | |
| SCHEMBL11748669 | 0.71 | CNR1 (0.68) | GAAMAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053483-A | DERIVATIVES OF 3,3-BIS-(4-HYDROXYPHENYL)-2-INDOLINONE AND PROCESS FOR THE PREPARATION THEREOF | DOCTOR ANDREU S.A. (ES) | 1977-10-11 | — | — | US | disclosed |