Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084369 | 0.92 | — | — | |
| SCHEMBL8525813 | 0.81 | — | — | |
| SCHEMBL12677766 | 0.79 | TSHR (0.46) | TSHRALDH1A1TDP1MAPT | |
| SCHEMBL11502617 | 0.76 | TSHR (0.30) | TSHR | |
| SCHEMBL19418605 | 0.75 | TSHR (0.42) | TSHRALDH1A1TDP1MAPT | |
| SCHEMBL12677771 | 0.75 | TSHR (0.42) | TSHRALDH1A1TDP1MAPT | |
| SCHEMBL3418812 | 0.75 | TSHR (0.42) | TSHRALDH1A1TDP1MAPT | |
| SCHEMBL12677768 | 0.75 | TSHR (0.42) | TSHRALDH1A1TDP1MAPT | |
| SCHEMBL19418606 | 0.75 | TSHR (0.42) | TSHRALDH1A1TDP1MAPT | |
| SCHEMBL22200073 | 0.75 | TSHR (0.37) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4003847-A | FOR FOAMING POLYETHERURETHANES; CYANOALKYL POLYSILOXANE; POLYETHER SOLVENT | UNION CARBIDE CORPORATION (US) | 1977-01-18 | — | — | US | disclosed |
| US-3952038-A | CYANOALKYL MODIFIED SILOXANE FLUID | UNION CARBIDE CORPORATION (US) | 1976-04-20 | — | — | US | disclosed |