Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11463073 | 0.83 | SLC18A3 (0.71) | SLC18A3SIGMAR1LTA4HHRH4HRH3 | |
| SCHEMBL6391373 | 0.80 | SLC18A3 (1.00) | SLC18A3SIGMAR1LTA4HHRH4HRH3 | |
| SCHEMBL6391371 | 0.80 | SLC18A3 (1.00) | SLC18A3SIGMAR1LTA4HHRH4HRH3 | |
| SCHEMBL9433040 | 0.80 | SLC18A3 (1.00) | SLC18A3SIGMAR1LTA4HHRH4HRH3 | |
| SCHEMBL11464581 | 0.79 | SLC18A3 (0.66) | SLC18A3SIGMAR1HRH4HRH3OPRM1 | |
| SCHEMBL11465060 | 0.78 | SLC18A3 (0.63) | SLC18A3SIGMAR1LTA4HHRH4HRH3 | |
| SCHEMBL11465061 | 0.78 | SLC18A3 (0.63) | SLC18A3SIGMAR1LTA4HHRH4HRH3 | |
| SCHEMBL12139118 | 0.78 | SLC18A3 (0.63) | SLC18A3SIGMAR1LTA4HHRH4HRH3 | |
| SCHEMBL13452424 | 0.78 | SLC18A3 (0.68) | SLC18A3SIGMAR1LTA4HHRH4HRH3 | |
| SCHEMBL11465059 | 0.78 | SLC18A3 (0.63) | SLC18A3SIGMAR1LTA4HHRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4003931-A | ANTIINFLAMMATORY AGENTS, ANALGESICS | FUVEAU S.A. (FR) | 1977-01-18 | — | — | US | disclosed |