Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 5/20 | 0.48 |
| ▸ | GHSR | Q92847 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 8/20 | 0.45 |
| ▸ | MMP1 | P03956 | 6/20 | 0.45 |
| ▸ | MMP9 | P14780 | 7/20 | 0.45 |
| ▸ | MMP8 | P22894 | 7/20 | 0.45 |
| ▸ | MMP3 | P08254 | 3/20 | 0.45 |
| ▸ | IL1RN | P18510 | 2/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.43 |
| ▸ | ADAM12 | O43184 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | MMP15 | P51511 | 1/20 | 0.43 |
| ▸ | MMP16 | P51512 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29425247 | 0.89 | ACE (0.52) | GHSRERAP2ACE | |
| SCHEMBL11642380 | 0.87 | CTSC (0.55) | CTSCMMP2MMP1MMP9MMP8 | |
| SCHEMBL30254445 | 0.87 | ACE (0.53) | ERAP2ACE | |
| SCHEMBL31259938 | 0.87 | ACE (0.57) | ACE | |
| SCHEMBL29973876 | 0.87 | ACE (0.57) | ACE | |
| SCHEMBL30628987 | 0.87 | ACE (0.57) | ACE | |
| SCHEMBL31259940 | 0.87 | ACE (0.57) | ACE | |
| SCHEMBL30628999 | 0.87 | ACE (0.57) | ACE | |
| SCHEMBL29577528 | 0.87 | ACE (0.57) | ACE | |
| SCHEMBL11497997 | 0.85 | ACE (0.60) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010149-A | PEPTIDE | SANKYO COMPANY LIMITED (JA) | 1977-03-01 | — | — | US | disclosed |