Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11748236 | 1.00 | TSHR (0.51) | TSHRHCAR2EPHX1ATMFAAH | |
| SCHEMBL8383264 | 0.88 | TSHR (0.58) | TSHRHCAR2EPHX1ATMFAAH | |
| SCHEMBL5612333 | 0.88 | TSHR (0.58) | TSHRHCAR2EPHX1ATMFAAH | |
| SCHEMBL8169063 | 0.88 | TSHR (0.58) | TSHRHCAR2EPHX1ATMFAAH | |
| SCHEMBL9313916 | 0.88 | TSHR (0.58) | TSHRHCAR2EPHX1ATMFAAH | |
| SCHEMBL5612339 | 0.88 | TSHR (0.58) | TSHRHCAR2EPHX1ATMFAAH | |
| SCHEMBL973521 | 0.84 | ATM (0.59) | TSHRHCAR2ATMNAAAALDH1A1 | |
| SCHEMBL9495093 | 0.84 | ATM (0.59) | TSHRHCAR2ATMNAAAALDH1A1 | |
| SCHEMBL2273956 | 0.84 | ATM (0.59) | TSHRHCAR2ATMNAAAALDH1A1 | |
| SCHEMBL27419094 | 0.83 | TSHR (0.53) | TSHRHCAR2EPHX1ATMFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4048130-A | COPOLYMERIZATION, UNSATURATED ACIDS | LONZA LTD. (CH) | 1977-09-13 | — | — | US | disclosed |