Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GALR2 | O43603 | 1/20 | 0.38 |
| ▸ | GLP1R | P43220 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12064867 | 0.85 | DPP4 (0.43) | DPP4LMNAPOLBGALR2GLP1R | |
| SCHEMBL11860427 | 0.83 | KMT2A (0.54) | DPP4LMNAPOLBGALR2GLP1R | |
| SCHEMBL11751270 | 0.83 | MEN1 (0.44) | DPP4POLBGLP1RMAPTKMT2A | |
| SCHEMBL11748160 | 0.82 | DPP4 (0.43) | DPP4LMNAPOLBGLP1RMAPT | |
| SCHEMBL11749510 | 0.79 | DPP4 (0.48) | DPP4LMNAGLP1RMAPTKMT2A | |
| SCHEMBL11753027 | 0.77 | DPP4 (0.47) | DPP4LMNAPOLBGLP1RMAPT | |
| SCHEMBL11855381 | 0.75 | MEN1 (0.59) | DPP4LMNAPOLBGLP1RKMT2A | |
| SCHEMBL11750552 | 0.75 | SMN1; SMN2 (0.48) | DPP4LMNAGLP1RMAPTKMT2A | |
| SCHEMBL12064766 | 0.72 | DPP4 (0.43) | DPP4LMNAPOLBGLP1RMAPT | |
| SCHEMBL11854675 | 0.70 | DPP4 (0.44) | DPP4LMNAPOLBGLP1RMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055411-A | 5-NITRO-PYRIMIDINES | CIBA-GEIGY CORPORATION (US) | 1977-10-25 | — | — | US | disclosed |
| US-3948914-A | PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1976-04-06 | — | — | US | disclosed |