Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | TERT | O14746 | 3/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | F7 | P08709 | 2/20 | 0.39 |
| ▸ | F3 | P13726 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29047320 | 1.00 | TSHR (0.62) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL11789343 | 0.98 | TSHR (0.58) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL10795897 | 0.96 | TSHR (0.70) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL11859418 | 0.96 | TSHR (0.70) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL6672214 | 0.96 | TSHR (0.70) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL19235335 | 0.96 | TSHR (0.70) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL11204358 | 0.90 | TSHR (0.61) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL11481123 | 0.90 | TSHR (0.61) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL8003634 | 0.89 | TSHR (0.52) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL9007405 | 0.89 | MAPT (0.58) | TSHRALDH1A1MAPTABCC4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4033901-A | FOR OLEFIN EPOXIDATION | TEXACO INC. (US) | 1977-07-05 | — | — | US | disclosed |