Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 10/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | RXRB | P28702 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11749158 | 0.96 | MAPK14 (0.47) | MAPK14MEN1KMT2ARXRARXRB | |
| SCHEMBL11753979 | 0.96 | MAPK14 (0.47) | MAPK14MEN1KMT2ARXRARXRB | |
| SCHEMBL11751581 | 0.88 | MAPK14 (0.49) | MAPK14MEN1KMT2ARXRARXRB | |
| SCHEMBL11755594 | 0.87 | MEN1 (0.39) | MAPK14MEN1KMT2ANPC1RXRA | |
| SCHEMBL11756240 | 0.83 | MAPK14 (0.44) | MAPK14MEN1KMT2ANPC1RXRA | |
| SCHEMBL11748651 | 0.83 | MAPK14 (0.44) | MAPK14MEN1KMT2ANPC1RXRA | |
| SCHEMBL8066719 | 0.83 | MAPK14 (0.56) | MAPK14MEN1KMT2ANPC1 | |
| SCHEMBL11752064 | 0.81 | ADORA2A (0.55) | MAPK14MEN1KMT2ARXRARXRB | |
| 2-Mercaptoethanol SCHEMBL11750992 | 0.78 | MAPK14 (0.45) | MAPK14MEN1KMT2ANPC1CNR1 | |
| SCHEMBL11748061 | 0.77 | MAPK14 (0.50) | MAPK14MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | claimed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | claimed |
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |