Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10707630 | 1.00 | EPHX1 (0.39) | EPHX1POLBMEN1KMT2AEGFR | |
| SCHEMBL31531964 | 0.81 | EPHX1 (0.39) | EPHX1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL18972850 | 0.77 | EPHX1 (0.38) | EPHX1POLBMEN1KMT2AEGFR | |
| SCHEMBL125890 | 0.72 | EPHX1 (0.34) | EPHX1ALDH1A1FFAR3 | |
| Tert-Butylamine SCHEMBL20503853 | 0.72 | EPHX1 (0.34) | EPHX1CYP2C9SMN1; SMN2ALDH1A1 | |
| SCHEMBL1509771 | 0.72 | EPHX1 (0.34) | EPHX1ALDH1A1FFAR3 | |
| SCHEMBL526285 | 0.72 | EPHX1 (0.34) | EPHX1ALDH1A1FFAR3 | |
| SCHEMBL669001 | 0.69 | KDM5B (0.42) | EPHX1POLBMEN1KMT2AEGFR | |
| SCHEMBL20659186 | 0.69 | — | — | |
| SCHEMBL6038209 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4042646-A | BETA-AMINO-ALPHA, BETA-UNSATURATED KETONE, POLYESTERS | NIHON YUSHI CO., LTD. (JA) | 1977-08-16 | — | — | US | claimed |