Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.60 |
| ▸ | TRPV1 | Q8NER1 | 13/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | PPARD | Q03181 | 1/20 | 0.54 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11753468 | 0.94 | HDAC3 (0.65) | HDAC3HDAC1TRPV1HDAC2NPC1 | |
| SCHEMBL11758482 | 0.94 | HDAC3 (0.65) | HDAC3HDAC1TRPV1HDAC2NPC1 | |
| SCHEMBL11761056 | 0.94 | HDAC3 (0.65) | HDAC3HDAC1TRPV1HDAC2NPC1 | |
| SCHEMBL11762085 | 0.94 | HDAC3 (0.65) | HDAC3HDAC1TRPV1HDAC2NPC1 | |
| SCHEMBL11758459 | 0.94 | HDAC3 (0.65) | HDAC3HDAC1TRPV1HDAC2NPC1 | |
| SCHEMBL11762106 | 0.94 | HDAC3 (0.65) | HDAC3HDAC1TRPV1HDAC2NPC1 | |
| SCHEMBL11761331 | 0.94 | HDAC3 (0.65) | HDAC3HDAC1TRPV1HDAC2NPC1 | |
| SCHEMBL11756763 | 0.94 | HDAC3 (0.65) | HDAC3HDAC1TRPV1HDAC2NPC1 | |
| SCHEMBL11759668 | 0.89 | TRPV1 (0.62) | HDAC3HDAC1TRPV1HDAC2NPC1 | |
| SCHEMBL11755757 | 0.89 | HDAC3 (0.66) | HDAC3HDAC1TRPV1HDAC2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4009208-A | N,N'-HEPTAMETHYLENEBIS(4-METHOXYBENZAMIDE) | STERLING DRUG INC. (US) | 1977-02-22 | — | — | US | disclosed |