Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | MLYCD | O95822 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11762106 | 0.88 | HDAC3 (0.65) | NPC1RAB9AMLYCDHDAC3HDAC1 | |
| SCHEMBL11756763 | 0.88 | HDAC3 (0.65) | NPC1RAB9AMLYCDHDAC3HDAC1 | |
| SCHEMBL11762085 | 0.88 | HDAC3 (0.65) | NPC1RAB9AMLYCDHDAC3HDAC1 | |
| SCHEMBL11758459 | 0.88 | HDAC3 (0.65) | NPC1RAB9AMLYCDHDAC3HDAC1 | |
| SCHEMBL11761331 | 0.88 | HDAC3 (0.65) | NPC1RAB9AMLYCDHDAC3HDAC1 | |
| SCHEMBL11758482 | 0.88 | HDAC3 (0.65) | NPC1RAB9AMLYCDHDAC3HDAC1 | |
| SCHEMBL11753468 | 0.88 | HDAC3 (0.65) | NPC1RAB9AMLYCDHDAC3HDAC1 | |
| SCHEMBL11761056 | 0.88 | HDAC3 (0.65) | NPC1RAB9AMLYCDHDAC3HDAC1 | |
| SCHEMBL11757212 | 0.86 | NPC1 (0.58) | NPC1RAB9AMLYCDHDAC3HDAC1 | |
| SCHEMBL11760414 | 0.84 | NPC1 (0.68) | NPC1RAB9AMLYCDHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4009208-A | N,N'-HEPTAMETHYLENEBIS(4-METHOXYBENZAMIDE) | STERLING DRUG INC. (US) | 1977-02-22 | — | — | US | disclosed |