Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | FGB | P02675 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9176658 | 0.83 | MEN1 (0.51) | MEN1KMT2APOLBFGBLMNA | |
| SCHEMBL9620077 | 0.82 | MEN1 (0.50) | MEN1KMT2APOLBFGBNPC1 | |
| SCHEMBL31718809 | 0.82 | MEN1 (0.50) | MEN1KMT2APOLBFGBNPC1 | |
| SCHEMBL10895437 | 0.80 | KCNA3 (0.52) | MEN1KMT2APOLBNPC1LMNA | |
| SCHEMBL11761817 | 0.80 | ADORA2A (0.44) | MEN1KMT2APOLBFGBNPC1 | |
| SCHEMBL12311505 | 0.79 | KCNA3 (0.54) | MEN1KMT2APOLBLMNARAB9A | |
| SCHEMBL11759366 | 0.79 | KCNA3 (0.58) | MEN1KMT2APOLBLMNARAB9A | |
| SCHEMBL28124672 | 0.79 | AURKA (0.47) | MEN1KMT2APOLBLMNAKDM4E | |
| SCHEMBL11762190 | 0.79 | ADORA2A (0.48) | MEN1KMT2APOLBFGBNPC1 | |
| SCHEMBL10609299 | 0.78 | MEN1 (0.45) | MEN1KMT2APOLBFGBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4008222-A | POLYESTERS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-15 | — | — | US | disclosed |