Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1472458 | 0.97 | SNCA (0.39) | SNCAGAAARPOLBKDM4E | |
| SCHEMBL1472499 | 0.97 | SNCA (0.39) | SNCAGAAARPOLBKDM4E | |
| SCHEMBL1472475 | 0.92 | SNCA (0.38) | SNCAGAAARPOLBKDM4E | |
| Iodide SCHEMBL3714596 | 0.92 | NOX1 (0.50) | SNCAGAAARPOLBKDM4E | |
| Iodide SCHEMBL3714593 | 0.92 | NOX1 (0.50) | SNCAGAAARPOLBKDM4E | |
| Iodide SCHEMBL3714591 | 0.92 | NOX1 (0.50) | SNCAGAAARPOLBKDM4E | |
| SCHEMBL1470385 | 0.91 | SNCA (0.37) | SNCAGAAARPOLBKDM4E | |
| SCHEMBL5725873 | 0.90 | SNCA (0.41) | SNCAGAAARPOLBKDM4E | |
| SCHEMBL1470945 | 0.90 | GAA (0.35) | SNCAGAAARPOLBKDM4E | |
| SCHEMBL12592413 | 0.90 | SNCA (0.43) | SNCAGAAARPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160051559-A1 | 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE | WISTA LABORATORIES LTD. (SG) | 2016-02-25 | — | — | US | disclosed |
| US-20160051559-A1 | 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE | WISTA LABORATORIES LTD. (SG) | 2016-02-25 | — | — | US | disclosed |
| US-9174954-B2 | 3,7-diamino-10H-phenothiazine salts and their use | WISTA LABORATORIES LTD. (SG) | 2015-11-03 | — | — | US | disclosed |
| US-9174954-B2 | 3,7-diamino-10H-phenothiazine salts and their use | WISTA LABORATORIES LTD. (SG) | 2015-11-03 | — | — | US | disclosed |
| US-20140221359-A1 | 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE | Wis Ta Laboratories Ltd. (SG) | 2014-08-07 | — | — | US | disclosed |
| US-20140221359-A1 | 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE | Wis Ta Laboratories Ltd. (SG) | 2014-08-07 | — | — | US | disclosed |
| US-20110118242-A1 | 3,7-DIAMINO-10H-PHINOTHIAZINE SALTS AND THEIR USE | WISTA LABORATORIES LTD. | 2011-05-19 | — | — | US | disclosed |
| US-7888350-B2 | 3,7-diamino-10H-phenothiazine salts and their use | WISTA LABORATORIES LTD. (SG) | 2011-02-15 | — | — | US | disclosed |
| US-20090054419-A1 | 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE | WISTA LABORATORIES LTD. | 2009-02-26 | — | — | US | disclosed |
| US-4017313-A | Photosensitive composition containing a leuco dye, a photosensitizer, an aromatic aldehyde and a secondary or tertiary amine and the use thereof in a direct-print process | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221359-A1 | 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE | PSEN1, PSEN2, APP | SNCA 517/4885GAA 2015/4885AR 4056/4885 |
| US-20110118242-A1 | 3,7-DIAMINO-10H-PHINOTHIAZINE SALTS AND THEIR USE | PSEN1, PSEN2, APP | SNCA 1937/4885GAA 3842/4885AR 4539/4885 |
| US-20160051559-A1 | 3, 7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE | PSEN1, PSEN2, APP | SNCA 673/4885GAA 2333/4885AR 4183/4885 |
| US-20090054419-A1 | 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE | PSEN1, PSEN2, HTT | SNCA 1049/4885GAA 3257/4885AR 4605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.