Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2242814 | 0.87 | PTPN1 (0.58) | PTPN1SMN1; SMN2KDM4EALDH1A1RAB9A | |
| SCHEMBL31598898 | 0.87 | PTPN1 (0.58) | PTPN1SMN1; SMN2KDM4EALDH1A1RAB9A | |
| SCHEMBL17281449 | 0.85 | KDM4E (0.59) | PTPN1SMN1; SMN2KDM4EALDH1A1RAB9A | |
| SCHEMBL2245016 | 0.84 | PTPN1 (0.56) | PTPN1SMN1; SMN2KDM4EALDH1A1RAB9A | |
| SCHEMBL27361204 | 0.84 | PTPN1 (0.56) | PTPN1SMN1; SMN2KDM4EALDH1A1RAB9A | |
| SCHEMBL29407182 | 0.84 | PTPN1 (0.56) | PTPN1SMN1; SMN2KDM4EALDH1A1RAB9A | |
| SCHEMBL29728166 | 0.84 | PTPN1 (0.56) | PTPN1SMN1; SMN2KDM4EALDH1A1RAB9A | |
| SCHEMBL27364394 | 0.83 | PTPN1 (0.55) | PTPN1SMN1; SMN2KDM4EALDH1A1RAB9A | |
| SCHEMBL7604878 | 0.83 | PTPN1 (0.55) | PTPN1SMN1; SMN2KDM4EALDH1A1RAB9A | |
| SCHEMBL2246230 | 0.80 | PTPN1 (0.63) | PTPN1SMN1; SMN2KDM4EALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4014870-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1977-03-29 | — | — | US | disclosed |