Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | GBA1 | P04062 | 2/20 | 0.37 |
| ▸ | DNTT | P04053 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10563094 | 1.00 | PPARG (0.42) | PPARGPPARDPPARAGBA1DNTT | |
| SCHEMBL11763240 | 0.98 | PPARG (0.40) | PPARGPPARDPPARAGBA1DNTT | |
| SCHEMBL11763379 | 0.94 | PPARG (0.36) | PPARGPPARDPPARADNTT | |
| SCHEMBL10559876 | 0.90 | PPARG (0.47) | PPARGPPARDPPARAGBA1DNTT | |
| SCHEMBL10561194 | 0.90 | PPARG (0.44) | PPARGPPARDPPARAGBA1DNTT | |
| SCHEMBL10562939 | 0.90 | PPARG (0.47) | PPARGPPARDPPARAGBA1DNTT | |
| SCHEMBL10564673 | 0.90 | PPARG (0.44) | PPARGPPARDPPARAGBA1DNTT | |
| SCHEMBL10561484 | 0.90 | PPARG (0.44) | PPARGPPARDPPARAGBA1DNTT | |
| SCHEMBL10559585 | 0.90 | PPARG (0.44) | PPARGPPARDPPARAGBA1DNTT | |
| SCHEMBL10558947 | 0.86 | PPARG (0.39) | PPARGPPARDPPARAGBA1DNTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4059595-A | Process for preparing 3-oxy-4H-pyran-4-one derivatives | OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHI (JA) | 1977-11-22 | — | — | US | disclosed |