SCHEMBL1176918

SCHEMBL1176918

C=CC(=O)OC(=N)OC(=O)C=C

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.40
ALDH1A1 P00352 7/20 0.40
TP53 P04637 3/20 0.40
HIF1A Q16665 3/20 0.40
CYP3A4 P08684 2/20 0.40
HSD17B10 Q99714 1/20 0.40
LMNA P02545 1/20 0.37
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HPGD P15428 1/20 0.36
FGFR4 P22455 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278164 0.83
SCHEMBL11652843 0.80
SCHEMBL1964383 0.80
SCHEMBL31635272 0.80 TSHR (0.43) TSHRALDH1A1TP53HIF1ACYP3A4
Magnesium SCHEMBL29890535 0.80 TSHR (0.43) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL30129042 0.80 TSHR (0.43) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL5071464 0.80 TSHR (0.43) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL29531095 0.80 TSHR (0.43) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL7076062 0.80 TSHR (0.43) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL30857469 0.80 TSHR (0.43) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5849833-A Method for improving drying speed in printing process and fast dry printing ink used therein ROHM AND HAAS COMPANY (US) 1998-12-15 US claimed
EP-0594321-B1 Aqueous composition ROHM & HAAS (US) 1997-03-05 EP claimed
EP-3645589-B1 STORAGE STABLE QUICKSETTING COATING SYSTEM THAT IS FREE OF VOLATILE-BASE ROHM & HAAS (US) 2022-01-19 EP disclosed
CN-110741023-B Storage stable fast setting coating system free of volatile base 罗门哈斯公司 2021-10-15 CN disclosed
US-11124669-B2 Storage stable quicksetting coating system that is free of volatile-base ROHM AND HAAS COMPANY (US) 2021-09-21 US disclosed
EP-3356480-B1 SHELF-STABLE AQUEOUS COMPOSITION AND PROCESS OF MAKING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2021-01-06 EP disclosed
US-10717879-B2 Shelf-stable aqueous composition and process of making the same DOW GLOBAL TECHNOLOGIES LLC (US) 2020-07-21 US disclosed
EP-3645589-A1 STORAGE STABLE QUICKSETTING COATING SYSTEM THAT IS FREE OF VOLATILE-BASE Rohm and Haas Company (US) 2020-05-06 EP disclosed
US-20200109308-A1 STORAGE STABLE QUICKSETTING COATING SYSTEM THAT IS FREE OF VOLATILE-BASE ROHM AND HAAS COMPANY 2020-04-09 US disclosed
CN-110741023-A Storage stable fast setting coating system free of volatile base 罗门哈斯公司 2020-01-31 CN disclosed
WO-2019005543-A1 STORAGE STABLE QUICKSETTING COATING SYSTEM THAT IS FREE OF VOLATILE-BASE ROHM AND HAAS COMPANY (US) 2019-01-03 WO disclosed
EP-0594321-B1 Aqueous composition ROHM & HAAS (US) 1997-03-05 EP disclosed
EP-0758673-A2 Method for improving drying speed in printing process and fast dry printing ink used therein ROHM AND HAAS COMPANY (US) 1997-02-19 EP disclosed
EP-0728822-A2 Aqueous paint composition ROHM AND HAAS COMPANY (US) 1996-08-28 EP disclosed
US-5527853-A ANIONIC POLYMERS OF AMINE-MODIFIED ACRYLIC ESTERS AND AMIDES WITH VOLATILE BASE TO ADJUST PH TO NON-IONIC STATE ROHM AND HAAS COMPANY (US) 1996-06-18 US disclosed
EP-0594321-A1 Aqueous composition ROHM AND HAAS COMPANY (US) 1994-04-27 EP disclosed
EP-0409459-A2 Aqueous coating compositions ROHM AND HAAS COMPANY (US) 1991-01-23 EP disclosed
US-4199400-A Migration-resistant binder compositions for bonding nonwoven fibers; also methods and articles ROHM AND HAAS COMPANY (US) 1980-04-22 US disclosed
US-4119600-A ANIONICALLY-STABILIZED POLYMER LATEX, WATER-SOLUBLE POLYMER, VOLATILE BASE ROHM AND HAAS COMPANY (US) 1978-10-10 US disclosed
US-4054717-A CLAYS, WATER SOLUBLE POLYMER HAVING AMINE GROUPS ROHM AND HAAS COMPANY (US) 1977-10-18 US disclosed