Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.66 |
| ▸ | TTR | P02766 | 6/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11770506 | 0.92 | AKR1B1 (0.64) | AKR1B1TTRLTB4RALDH1A1KMT2A | |
| SCHEMBL11769373 | 0.91 | AKR1B1 (0.61) | AKR1B1TTRLTB4RALDH1A1TP53 | |
| SCHEMBL11767628 | 0.89 | AKR1B1 (0.52) | AKR1B1TTRLTB4RALDH1A1KMT2A | |
| SCHEMBL11770899 | 0.89 | AKR1B1 (0.52) | AKR1B1TTRLTB4RALDH1A1KMT2A | |
| SCHEMBL11766582 | 0.89 | AKR1B1 (0.52) | AKR1B1TTRLTB4RALDH1A1KMT2A | |
| SCHEMBL11770514 | 0.89 | AKR1B1 (0.70) | AKR1B1TTRLTB4RALDH1A1KMT2A | |
| SCHEMBL11775067 | 0.88 | AKR1B1 (0.51) | AKR1B1TTRLTB4RALDH1A1KMT2A | |
| SCHEMBL11766480 | 0.88 | AKR1B1 (0.51) | AKR1B1TTRLTB4RALDH1A1KMT2A | |
| SCHEMBL11770426 | 0.86 | AKR1B1 (0.49) | AKR1B1TTRLTB4RALDH1A1KMT2A | |
| SCHEMBL11772138 | 0.86 | AKR1B1 (0.49) | AKR1B1TTRLTB4RALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3989721-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-11-02 | — | — | US | disclosed |
| US-3989720-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-11-02 | — | — | US | disclosed |
| US-3988352-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-10-26 | — | — | US | disclosed |
| US-3979414-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-09-07 | — | — | US | disclosed |
| US-3965115-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-06-22 | — | — | US | disclosed |
| US-3963753-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-06-15 | — | — | US | disclosed |
| US-3963752-A | Disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-06-15 | — | — | US | disclosed |